Yes, in 2023 stock markets in The United States are open on the day before Thanksgiving, Wednesday, November 22.
The United States Stock Market will be Open on the day before Thanksgiving, Wednesday, November 22nd. The day before Thanksgiving Day is not considered a holiday. The stock market will be open with normal trading hours on this day. However, the market will be closed on Thanksgiving Day, and have reduced hours on the day after Thanksgiving. On that Friday the market closes early at 1pm EST.
Source 1 - https://www.nyse.com/markets/hours-calendars